Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316646 | 0.85 | MEN1 (0.49) | KDM4EMAPK1ALDH1A1POLBALOX15 | |
| SCHEMBL9316047 | 0.81 | GPR119 (0.40) | KDM4EALDH1A1HTT | |
| SCHEMBL10481976 | 0.79 | MAPT (0.53) | MAPK1ALDH1A1POLBMCL1MAPT | |
| SCHEMBL9315594 | 0.78 | PARP1 (0.36) | ALOX15HSD17B10MAPTGAAMEN1 | |
| SCHEMBL9315615 | 0.73 | PTGDR2 (0.48) | MAPK1ALOX15MCL1MAPTGAA | |
| SCHEMBL9315614 | 0.73 | PTGDR2 (0.48) | MAPK1ALOX15MCL1MAPTGAA | |
| SCHEMBL9316061 | 0.73 | BAZ2B (0.45) | KDM4EMAPK1ALDH1A1MCL1MAPT | |
| SCHEMBL9314844 | 0.71 | CFTR (0.42) | MAPK1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9314695 | 0.71 | TRPV1 (0.47) | MAPK1ALDH1A1ALOX15HSD17B10MCL1 | |
| SCHEMBL9314846 | 0.70 | BAZ2B (0.46) | KDM4EMAPK1ALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281608-A | Antiinflammatory agents and interleukin II antagonist | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |