Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutarate SCHEMBL9317226 | 0.97 | NPC1 (0.50) | NPC1RAB9AHPGDMEN1KMT2A | |
| Succinic Acid SCHEMBL9316978 | 0.90 | NPC1 (0.53) | NPC1RAB9AHPGDMEN1KMT2A | |
| Behenic Acid SCHEMBL9316970 | 0.89 | CES2 (0.51) | NPC1RAB9AHPGDEPHX1ALDH1A1 | |
| Stearic Acid SCHEMBL9317247 | 0.89 | CES2 (0.51) | NPC1RAB9AHPGDEPHX1ALDH1A1 | |
| Stearic Acid SCHEMBL9317214 | 0.86 | CES2 (0.51) | NPC1RAB9AHPGDEPHX1ALDH1A1 | |
| Glutarate SCHEMBL9316643 | 0.84 | NPC1 (0.53) | NPC1RAB9AHPGDMEN1KMT2A | |
| Acetic Acid SCHEMBL9317240 | 0.83 | NPC1 (0.61) | NPC1RAB9AHPGDMEN1KMT2A | |
| Benzoic Acid SCHEMBL9317253 | 0.83 | NPC1 (0.56) | NPC1RAB9AHPGDMEN1KMT2A | |
| Glutarate SCHEMBL9469147 | 0.82 | ALDH1A1 (0.59) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| Acetic Acid SCHEMBL9318271 | 0.80 | NPC1 (0.61) | NPC1RAB9AHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354514-A | Heating mixture of thioamide compound and copper- or lead-containing compound | JUJO PAPER CO., LTD. (JP) | 1994-10-11 | — | — | US | disclosed |