⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706081 | 0.92 | — | — | |
| SCHEMBL7260301 | 0.90 | DGKA (0.61) | — | |
| SCHEMBL7647987 | 0.90 | DGKA (0.61) | — | |
| SCHEMBL2189614 | 0.90 | DGKA (0.61) | — | |
| SCHEMBL926254 | 0.90 | DGKA (0.61) | — | |
| SCHEMBL10642835 | 0.90 | DGKA (0.61) | — | |
| SCHEMBL2029048 | 0.90 | DGKA (0.61) | — | |
| SCHEMBL9844549 | 0.90 | DGKA (0.61) | — | |
| SCHEMBL4152672 | 0.90 | DGKA (0.61) | — | |
| SCHEMBL539005 | 0.90 | DGKA (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104402782-B | The synthetic method of 2-[(4-dodecyloxy phenyl) sulfuryl] butyric acid | JIANGXI RENMING PHARMACEUTICAL CHEMICAL INDUSTRY CO., LTD. (CN) | 2016-01-27 | — | — | CN | claimed |
| CN-102952088-B | Preparation method of dexrazoxane | JIANGSU AOSAIKANG PHARM CO LTD | 2015-05-27 | — | — | CN | claimed |
| CN-104402782-A | 2-[(4-dodecyloxy phenyl) sulfuryl] butyric acid synthetic method | JIANGXI RENMING MEDICINE CHEMICAL CO LTD | 2015-03-11 | — | — | CN | claimed |
| CN-102952088-A | Preparation method of dexrazoxane | JIANGSU AOSAIKANG PHARM CO LTD | 2013-03-06 | — | — | CN | claimed |
| CN-101575300-B | Production method of S-2-aminobutanamide | UNIV SHAOXING | 2012-10-03 | — | — | CN | claimed |
| CN-101565379-B | Preparation method of L-homoserine hydrochloride | Zhejiang Artex Fiber Co., Ltd. (CN) | 2012-02-01 | — | — | CN | claimed |
| CN-101782719-A | Ink-jet resist agent | ADVANCE MATERIALS CORP | 2010-07-21 | — | — | CN | claimed |
| CN-101575300-A | Production method of S-2-aminobutanamide | UNIV SHAOXING (CN) | 2009-11-11 | — | — | CN | claimed |
| CN-101565379-A | Preparation method of L-homoserine hydrochloride | ZHEJIANG ARTEX FIBER CO LTD (CN) | 2009-10-28 | — | — | CN | claimed |
| CN-114853603-A | Research on copper-catalyzed construction of iodo-alkyl ester compound from cyclic ether and carboxylic acid | 湖南大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-109432508-B | Decalcified bone matrix material with bone growth promoting and antibacterial functions as well as preparation method and application thereof | 中国人民解放军总医院第一附属医院 | 2021-05-28 | — | — | CN | disclosed |
| EP-3728216-A1 | PYRAZOLE N-LINKED CARBAMOYL CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2020-10-28 | — | — | EP | disclosed |
| CN-108785305-A | The heterocycle inhibitor of glutaminase | 卡利泰拉生物科技公司 | 2018-11-13 | — | — | CN | disclosed |
| CN-104402782-B | The synthetic method of 2-[(4-dodecyloxy phenyl) sulfuryl] butyric acid | JIANGXI RENMING PHARMACEUTICAL CHEMICAL INDUSTRY CO., LTD. (CN) | 2016-01-27 | — | — | CN | disclosed |
| CN-1016507-B | Process for preparation of forskolin derivatives | NIPPON KAYAKU KK (JP) | 1992-05-06 | — | — | CN | disclosed |
| US-5017656-A | Adding A Carboxylic Acid | GENERAL ELECTRIC COMPANY (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0378468-A2 | Derivatives of bisaryl alkenes, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1990-07-18 | — | — | EP | disclosed |
| CN-1007893-B | Process for preparation of ether matrix of anti-inflammatory oxacikam | PFIZER (US) | 1990-05-09 | — | — | CN | disclosed |
| CN-86107826-A | New forskrine derivant | — | 1987-10-14 | — | — | CN | disclosed |
| CN-85102030-A | The preparation method of the ethers parent medicine of antiphlogiston Xi Kamu | — | 1987-01-31 | — | — | CN | disclosed |