Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.51 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | NCS1 | P62166 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912351 | 0.82 | PKM (0.54) | PKMLOXL2HPGDHSD17B10CYP1A2 | |
| SCHEMBL6177984 | 0.80 | PKM (0.75) | PKMLOXL2HPGDHSD17B10CYP1A2 | |
| SCHEMBL15149247 | 0.79 | LOXL2 (0.63) | PKMLOXL2HPGDHSD17B10CYP1A2 | |
| SCHEMBL2856934 | 0.79 | HPGD (0.56) | PKMLOXL2HPGDHSD17B10CYP1A2 | |
| SCHEMBL25832641 | 0.79 | LOXL2 (0.59) | PKMLOXL2HPGDHSD17B10CYP1A2 | |
| SCHEMBL11243380 | 0.79 | PKM (0.54) | PKMLOXL2HPGDHSD17B10CYP1A2 | |
| SCHEMBL8088125 | 0.79 | LOXL2 (0.67) | PKMLOXL2HPGDHSD17B10CYP1A2 | |
| SCHEMBL9443162 | 0.78 | LOXL2 (0.54) | PKMLOXL2HPGDHSD17B10CYP1A2 | |
| SCHEMBL6177774 | 0.77 | PKM (0.77) | PKMALOX5SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL30944811 | 0.77 | PKM (0.52) | PKMLOXL2HPGDHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278166-A | 4-amino-3-heteroaryl butyric acid compounds, compositions, and their use for treating disorders involving a dysfunction of GABAB receptors | ADIR ET COMPAGNIE (FR) | 1994-01-11 | — | — | US | disclosed |
| US-5214063-A | 4-aminobutyric acid compounds, compositions and methods of use for treating disorders related to a dysfunction of GABAB receptors | ADIR ET COMPAGNIE (FR) | 1993-05-25 | — | — | US | disclosed |
| US-5162364-A | Treatment of spastic and senescence disorders | ADIR ET COMPAGNIE (FR) | 1992-11-10 | — | — | US | disclosed |