Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452675 | 0.81 | CA1 (0.58) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9254186 | 0.78 | GSK3B (0.50) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9316427 | 0.78 | CA1 (0.52) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6072613 | 0.76 | ALDH1A1 (0.61) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4452972 | 0.74 | CA1 (0.62) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27351688 | 0.73 | CA1 (0.64) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6321927 | 0.73 | ALOX5 (0.62) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13531982 | 0.72 | GSK3B (0.61) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4456578 | 0.72 | CA1 (0.58) | ALDH1A1MAPTMEN1KMT2ACES2 | |
| SCHEMBL16398970 | 0.72 | ALOX5 (0.92) | ALOX5ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314815-A | Method for temporarily inhibiting or deactivating serine hydrolase and adduct of serine hydrolase with a phosphonate or phosphate compound | THE CATHOLIC UNIVERSITY OF AMERICA (US) | 1994-05-24 | — | — | US | disclosed |
| US-5281523-A | Adduct of serine hydrolase and nitrophenyl pnenacyl phosphonate | THE CATHOLIC UNIVERSITY OF AMERICA (US) | 1994-01-25 | — | — | US | disclosed |