SCHEMBL9317128

SCHEMBL9317128

C=C(C)C(=O)OCCOc1ccc(N=Nc2ccc(S(=O)(=O)C[C@H](C)CC)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MMP13 P45452 2/20 0.37
MMP1 P03956 2/20 0.37
PPARA Q07869 9/20 0.36
PPARG P37231 4/20 0.35
PPARD Q03181 3/20 0.35
AOC2 O75106 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
THRB P10828 1/20 0.34
MMP3 P08254 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317132 1.00 POLB (0.41) POLBAPEX1HTTTDP1MMP13
SCHEMBL9317124 1.00 POLB (0.41) POLBAPEX1HTTTDP1MMP13
SCHEMBL9317069 0.94 HTT (0.50) POLBAPEX1HTTTDP1MMP13
SCHEMBL9318842 0.88 POLB (0.41) POLBAPEX1HTTTDP1MMP13
SCHEMBL9318847 0.88 POLB (0.41) POLBAPEX1HTTTDP1MMP13
SCHEMBL9317116 0.85 THRB (0.46) MMP13MMP1PPARAPPARGPPARD
SCHEMBL9317109 0.85 THRB (0.46) MMP13MMP1PPARAPPARGPPARD
SCHEMBL9317122 0.85 THRB (0.46) MMP13MMP1PPARAPPARGPPARD
SCHEMBL9317101 0.84 MMP13 (0.32) MMP13MMP1THRB
SCHEMBL9769528 0.84 MMP13 (0.32) MMP13MMP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed