SCHEMBL9317299

SCHEMBL9317299

S=C(c1ccccc1)N(c1ccccc1)c1cccc2ccccc12.[Pb]

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
MAPT P10636 2/20 0.59
KMT2A Q03164 2/20 0.59
MEN1 O00255 1/20 0.59
GAA P10253 1/20 0.59
HPGD P15428 1/20 0.59
SIGMAR1 Q99720 8/20 0.55
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2D6 P10635 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
HSP90AA1 P07900 1/20 0.38
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317256 0.97 ALDH1A1 (0.59) ALDH1A1L3MBTL1MAPTKMT2AMEN1
SCHEMBL13007114 0.80 SIGMAR1 (0.58) ALDH1A1L3MBTL1MAPTKMT2AMEN1
SCHEMBL4869612 0.79 SIGMAR1 (0.56) ALDH1A1L3MBTL1MAPTKMT2AMEN1
SCHEMBL3767488 0.79 SIGMAR1 (0.56) ALDH1A1L3MBTL1MAPTKMT2AMEN1
SCHEMBL3069182 0.77 SIGMAR1 (0.53) ALDH1A1L3MBTL1MAPTKMT2ASIGMAR1
SCHEMBL28613770 0.76 ALDH1A1 (1.00) ALDH1A1L3MBTL1MAPTKMT2AMEN1
SCHEMBL28821130 0.76 SIGMAR1 (0.61) ALDH1A1L3MBTL1KMT2ASIGMAR1CYP1A2
SCHEMBL1794802 0.75 SIGMAR1 (0.52) ALDH1A1L3MBTL1MAPTKMT2AMEN1
SCHEMBL6582932 0.73 SIGMAR1 (0.61) ALDH1A1L3MBTL1MAPTGAAHPGD
SCHEMBL6743206 0.72 SIGMAR1 (0.51) ALDH1A1L3MBTL1KMT2AGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5354514-A Heating mixture of thioamide compound and copper- or lead-containing compound JUJO PAPER CO., LTD. (JP) 1994-10-11 US disclosed