SCHEMBL9317372

SCHEMBL9317372

C=C(C)C(=O)OCCCCCCN(C)c1ccc(N=Nc2ccc(S(=O)(=O)C[C@H](C)CC)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
MMP14 P50281 1/20 0.36
POLB P06746 2/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA12 O43570 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
F2 P00734 2/20 0.32
PRSS1 P07477 2/20 0.32
PRSS2 P07478 2/20 0.32
PRSS3 P35030 2/20 0.32
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317369 1.00 TSHR (0.36) TSHRMMP14POLBAPEX1HTT
SCHEMBL9318862 0.93 CA12 (0.35) MMP14POLBCA12CA2CA9
SCHEMBL9318856 0.93 CA12 (0.35) MMP14POLBCA12CA2CA9
SCHEMBL9318860 0.93 CA12 (0.35) MMP14POLBCA12CA2CA9
SCHEMBL9317067 0.87 MMP14 (0.36) TSHRMMP14POLBCA12CA2
SCHEMBL9317056 0.87 MMP14 (0.36) TSHRMMP14POLBCA12CA2
SCHEMBL9317060 0.87 MMP14 (0.36) TSHRMMP14POLBCA12CA2
SCHEMBL9317808 0.87 TSHR (0.36) TSHRMMP14POLBAPEX1HTT
SCHEMBL10385312 0.86 MMP14 (0.35) MMP14POLBCA12CA2CA9
SCHEMBL9317069 0.86 HTT (0.50) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed