SCHEMBL9318862

SCHEMBL9318862

C=C(C)C(=O)OCCN(C)c1ccc(/N=N/c2ccc(S(=O)(=O)C[C@H](C)CC)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.35
CA2 P00918 3/20 0.35
CA9 Q16790 3/20 0.35
MMP14 P50281 1/20 0.34
F2 P00734 3/20 0.34
PRSS1 P07477 3/20 0.34
PRSS2 P07478 3/20 0.34
PRSS3 P35030 3/20 0.34
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.32
MMP13 P45452 2/20 0.31
MMP1 P03956 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9318856 1.00 CA12 (0.35) CA12CA2CA9MMP14F2
SCHEMBL9318860 1.00 CA12 (0.35) CA12CA2CA9MMP14F2
SCHEMBL9317369 0.93 TSHR (0.36) CA12CA2CA9MMP14F2
SCHEMBL9317372 0.93 TSHR (0.36) CA12CA2CA9MMP14F2
SCHEMBL9316911 0.88 ALDH1A1 (0.33) MEN1POLBKMT2AMMP13MMP1
SCHEMBL9316914 0.88 ALDH1A1 (0.33) MEN1POLBKMT2AMMP13MMP1
SCHEMBL9318762 0.86 CA12 (0.35) CA12CA2CA9MMP14F2
SCHEMBL9318766 0.86 CA12 (0.35) CA12CA2CA9MMP14F2
SCHEMBL9318773 0.86 CA12 (0.35) CA12CA2CA9MMP14F2
SCHEMBL9661479 0.83 CA12 (0.40) CA12CA2CA9MMP14F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed