Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KLK7 | P49862 | 2/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.42 |
| ▸ | CHRNG | P07510 | 2/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.42 |
| ▸ | CHRND | Q07001 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317633 | 0.87 | TPSAB1 (0.51) | TPSAB1TPSD1TPSG1MAPTKLK7 | |
| SCHEMBL28902002 | 0.79 | KLK7 (0.59) | MAPTKLK7KLK5FOLH1ABCB1 | |
| SCHEMBL28902004 | 0.79 | KLK7 (0.59) | MAPTKLK7KLK5FOLH1ABCB1 | |
| SCHEMBL29051005 | 0.77 | ACE (0.41) | KLK5CTSLCTSBCTSSCTSK | |
| SCHEMBL28620363 | 0.77 | AKT1 (0.47) | TPSAB1TPSD1TPSG1MAPTKLK5 | |
| SCHEMBL9389258 | 0.75 | FOLH1 (0.61) | FOLH1CPB1CPB2 | |
| SCHEMBL10799819 | 0.74 | TPSAB1 (0.51) | TPSAB1TPSD1TPSG1MAPTKLK7 | |
| SCHEMBL10746894 | 0.74 | MAPT (0.47) | TPSAB1TPSD1TPSG1MAPTKLK7 | |
| SCHEMBL15976615 | 0.73 | CA1 (0.66) | FOLH1CPB1CPB2 | |
| SCHEMBL23113656 | 0.73 | FOLH1 (0.71) | FOLH1CPB1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H1312-H | Method for the preparation of gyk-dtpa | CYTOGEN CORPORATION (US) | 1994-05-03 | — | — | US | disclosed |