Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28922741 | 0.83 | AKT1 (0.56) | AKT1MAOAITGA4ITGB7ACE | |
| SCHEMBL28922739 | 0.83 | AKT1 (0.56) | AKT1MAOAITGA4ITGB7ACE | |
| SCHEMBL28620920 | 0.80 | MGLL (0.36) | AKT1TPSAB1TPSD1TPSG1MAPT | |
| SCHEMBL28620369 | 0.78 | AKT1 (0.41) | AKT1TDP1POLBMAPTMEN1 | |
| SCHEMBL28624848 | 0.78 | AKT1 (0.41) | AKT1TDP1POLBMAPTMEN1 | |
| SCHEMBL29051005 | 0.77 | ACE (0.41) | ITGA4ITGB7ACEKLK5MEN1 | |
| Trifluoroacetic Acid SCHEMBL3048271 | 0.77 | AKT1 (0.42) | AKT1ACE | |
| SCHEMBL9317429 | 0.77 | TPSAB1 (0.48) | KLK5TPSAB1TPSD1TPSG1POLB | |
| Trifluoroacetic Acid SCHEMBL22207651 | 0.76 | AKT1 (0.43) | AKT1MAOATDP1POLBMAPT | |
| Trifluoroacetic Acid SCHEMBL22207652 | 0.76 | AKT1 (0.43) | AKT1MAOATDP1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301920-A | Complexes comprising ligands, spacers, peptide linkers and biomolecules | 安斯泰来制药株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-113271973-A | Complex comprising a ligand and a CEACAM5 antibody Fab fragment | 安斯泰来制药株式会社 | 2021-08-17 | — | — | CN | disclosed |