SCHEMBL9317445

SCHEMBL9317445

C=C(C)C(=O)OCCCCCCOc1ccc(C=Cc2ccc(S(=O)(=O)C[C@H](C)CC)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
APEX1 P27695 1/20 0.50
HTT P42858 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
TSHR P16473 2/20 0.40
ALB P02768 1/20 0.39
MMP1 P03956 2/20 0.39
HDAC3 O15379 1/20 0.39
STAT3 P40763 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
MMP3 P08254 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9318847 0.94 POLB (0.41) POLBAPEX1HTTTDP1MMP1
SCHEMBL9318842 0.94 POLB (0.41) POLBAPEX1HTTTDP1MMP1
SCHEMBL9317069 0.88 HTT (0.50) POLBAPEX1HTTTDP1TSHR
SCHEMBL9317704 0.87 POLB (0.45) POLBAPEX1HTTTDP1TSHR
SCHEMBL10385873 0.87 TSHR (0.38) POLBAPEX1HTTTDP1TSHR
SCHEMBL9317440 0.87 ALB (0.40) HTTTSHRALBMMP1HDAC3
SCHEMBL9098905 0.84 POLB (0.55) POLBAPEX1HTTTDP1TSHR
SCHEMBL9317129 0.83 POLB (0.58) POLBAPEX1HTTTDP1TSHR
SCHEMBL9316992 0.83 MMP13 (0.33) TSHRMMP1MMP13
SCHEMBL9316989 0.83 MMP13 (0.33) TSHRMMP1MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed