SCHEMBL9317440

SCHEMBL9317440

C=CC(=O)OCCCCCCOc1ccc(C=Cc2ccc(S(=O)(=O)C[C@H](C)CC)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALB P02768 1/20 0.40
THRB P10828 1/20 0.40
MMP1 P03956 2/20 0.39
TSHR P16473 2/20 0.39
HPGD P15428 1/20 0.39
HDAC3 O15379 1/20 0.39
STAT3 P40763 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
MMP3 P08254 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317485 0.94 THRB (0.47) THRBMMP1TSHRHPGDMMP3
SCHEMBL9317490 0.94 THRB (0.47) THRBMMP1TSHRHPGDMMP3
SCHEMBL9317448 0.89 THRB (0.39) THRBMMP1TSHRHPGDALDH1A1
SCHEMBL9317444 0.89 THRB (0.39) THRBMMP1TSHRHPGDALDH1A1
SCHEMBL10386950 0.87 TSHR (0.36) TSHRHPGDHDAC3HDAC4HDAC1
SCHEMBL9317418 0.87 MMP1 (0.40) ALBTHRBMMP1TSHRHPGD
SCHEMBL10386951 0.87 TSHR (0.36) TSHRHPGDHDAC3HDAC4HDAC1
SCHEMBL9317445 0.87 POLB (0.50) ALBMMP1TSHRHDAC3STAT3
SCHEMBL9100502 0.83 MMP1 (0.51) THRBMMP1TSHRHPGDMMP3
SCHEMBL9318756 0.82 THRB (0.47) ALBTHRBTSHRHPGDHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed