Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4642323 | 0.85 | ALPI (0.49) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL9318068 | 0.79 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1TDP1MEN1 | |
| SCHEMBL8710843 | 0.78 | TSHR (0.46) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL11397527 | 0.77 | LTA4H (0.54) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL216480 | 0.76 | ALPI (0.54) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL2734875 | 0.76 | ALPI (0.54) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL11789650 | 0.76 | TSHR (0.50) | SLC1A1TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL15015758 | 0.75 | TSHR (0.51) | SLC1A3SLC1A2SLC1A1TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL5281599 | 0.75 | ALPI (0.53) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL216479 | 0.75 | ALPI (0.53) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625141-A1 | AMINO ACID DERIVATIVES WITH ANTICHOLECYSTOKININ ACTIVITY. | BLACK JAMES FOUNDATION (GB) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993014066-A1 | AMINO ACID DERIVATIVES WITH ANTICHOLECYSTOKININ ACTIVITY | JAMES BLACK FOUNDATION LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |