Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841464 | 0.93 | SLC1A1 (0.57) | SLC1A3SLC1A2SLC1A1SLC7A5ATM | |
| SCHEMBL11387995 | 0.85 | SLC7A5 (0.51) | SLC1A3SLC1A2SLC1A1SLC7A5ATM | |
| SCHEMBL11836304 | 0.83 | ITGA4 (0.47) | ITGA4ITGB7MEN1KMT2AMAPT | |
| SCHEMBL7813695 | 0.82 | SLC1A1 (0.64) | SLC1A3SLC1A2SLC1A1SLC7A5ATM | |
| SCHEMBL15268441 | 0.82 | SLC1A1 (0.64) | SLC1A3SLC1A2SLC1A1SLC7A5ATM | |
| SCHEMBL27773551 | 0.82 | SLC1A1 (0.64) | SLC1A3SLC1A2SLC1A1SLC7A5ATM | |
| SCHEMBL9316759 | 0.79 | SLC1A1 (0.50) | SLC1A3SLC1A2SLC1A1SLC7A5ATM | |
| SCHEMBL9317573 | 0.79 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1SLC7A5ALPI | |
| SCHEMBL9316248 | 0.79 | SLC1A1 (0.50) | SLC1A3SLC1A2SLC1A1SLC7A5ATM | |
| SCHEMBL9841920 | 0.79 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1SLC7A5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625141-A1 | AMINO ACID DERIVATIVES WITH ANTICHOLECYSTOKININ ACTIVITY. | BLACK JAMES FOUNDATION (GB) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993014066-A1 | AMINO ACID DERIVATIVES WITH ANTICHOLECYSTOKININ ACTIVITY | JAMES BLACK FOUNDATION LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |