Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317882 | 0.90 | PPARG (0.55) | ALDH1A1MAPK1L3MBTL1PPARGPPARA | |
| SCHEMBL11104059 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1PPARGPPARA | |
| SCHEMBL11109284 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPK1L3MBTL1PPARGPPARA | |
| SCHEMBL11102275 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPK1L3MBTL1PPARGPPARA | |
| SCHEMBL7324487 | 0.82 | HTT (0.55) | ALDH1A1MAPK1L3MBTL1TDP1TSHR | |
| SCHEMBL27711548 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1PPARGPPARA | |
| SCHEMBL6687005 | 0.81 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL1567252 | 0.81 | TSHR (0.52) | ALDH1A1L3MBTL1PPARGPPARAKMT2A | |
| SCHEMBL6375356 | 0.80 | FOLH1 (0.53) | ALDH1A1KMT2ATSHRFOLH1TP53 | |
| SCHEMBL18556313 | 0.80 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281721-A | Substituted carboxy- or carbonyl sulfide-containing 2-benzopyran or 2-benzothiopyran derivatives | GEORGIA TECH RESEARCH CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |
| US-5109018-A | Emphysema therapy | GEORGIA TECH RESEARCH CORPORATION (US) | 1992-04-28 | — | — | US | disclosed |
| US-4596822-A | Chromene or thiochromene ring containing enzyme inhibitor | GEORGIA TECH RESEARCH CORPORATION (US) | 1986-06-24 | — | — | US | disclosed |