SCHEMBL6375356

SCHEMBL6375356

O=C(Cc1ccccc1C(=O)O)OC(=O)Cc1ccccc1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.53
ALDH1A1 P00352 7/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.49
TP53 P04637 1/20 0.47
HTT P42858 1/20 0.47
GAA P10253 1/20 0.46
HIF1A Q16665 2/20 0.44
CYP2C9 P11712 1/20 0.44
KDM4E B2RXH2 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
HMGB1 P09429 1/20 0.43
HPGD P15428 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA7 P43166 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6375365 0.89 ALDH1A1 (0.47) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL3916488 0.85 FOLH1 (0.50) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL29140649 0.83 FOLH1 (0.47) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL1567252 0.82 TSHR (0.52) FOLH1ALDH1A1TSHRSMN1; SMN2KMT2A
SCHEMBL9092886 0.82 KDM4E (0.58) FOLH1ALDH1A1ALOX15TSHRTP53
2-Carboxybenzeneacetic Acid SCHEMBL27477 0.81 AKR1B1 (0.61) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL6530167 0.81 FOLH1 (0.59) FOLH1ALDH1A1ALOX15TSHRTP53
2-Carboxybenzeneacetic Acid SCHEMBL1891118 0.81 AKR1B1 (0.61) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL9317809 0.80 ALDH1A1 (0.66) FOLH1ALDH1A1TSHRTP53HTT
2-Carboxybenzeneacetic Acid SCHEMBL3975685 0.79 BCAT2 (0.59) FOLH1ALDH1A1ALOX15TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220119584-A1 Degradable Urethane and Urethane-Urea Systems LANXESS CORPORATION (US) 2022-04-21 US claimed
EP-3921382-A1 DEGRADABLE URETHANE AND URETHANE-UREA SYSTEMS LANXESS Corporation (US) 2021-12-15 EP claimed
WO-2020163674-A1 DEGRADABLE URETHANE AND URETHANE-UREA SYSTEMS LANXESS SOLUTIONS US INC. (US) 2020-08-13 WO claimed
EP-0836627-B2 POLYMER MATERIAL, PROCESS FOR ITS PRODUCTION AND USE THEREOF BIO COMPOSITES AND MORE GMBH (DE) 2005-06-01 EP claimed
EP-0836627-B1 POLYMER MATERIAL, PROCESS FOR ITS PRODUCTION AND USE THEREOF PREFORM RAUMGLIEDERUNGSSYSTEME (DE) 2001-10-17 EP claimed
CN-113980017-B Synthesis method of C-13 methyl substituted tetrahydrochysene 13 methyl berberine derivative 四川大学 2023-05-05 CN disclosed
US-20220119584-A1 Degradable Urethane and Urethane-Urea Systems LANXESS CORPORATION (US) 2022-04-21 US disclosed
EP-3921382-A1 DEGRADABLE URETHANE AND URETHANE-UREA SYSTEMS LANXESS Corporation (US) 2021-12-15 EP disclosed
WO-2020163674-A1 DEGRADABLE URETHANE AND URETHANE-UREA SYSTEMS LANXESS SOLUTIONS US INC. (US) 2020-08-13 WO disclosed