Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317652 | 0.92 | ITGB3 (0.45) | ITGB3ITGA2BPRMT5WDR77GABRA1 | |
| SCHEMBL7332811 | 0.88 | CNR1 (0.42) | ITGB3ITGA2BL3MBTL1MEN1KMT2A | |
| SCHEMBL7328382 | 0.84 | ITGB3 (0.47) | ITGB3ITGA2BGABRA1GABRG2GABRB3 | |
| SCHEMBL9317817 | 0.84 | ITGB3 (0.51) | ITGB3ITGA2BPRMT5WDR77HDAC6 | |
| SCHEMBL7326953 | 0.82 | ITGB3 (0.58) | ITGB3ITGA2BGABRA1GABRG2GABRB3 | |
| SCHEMBL9317712 | 0.81 | ITGB3 (0.57) | ITGB3ITGA2BPRMT5WDR77 | |
| SCHEMBL8837011 | 0.80 | ITGB3 (0.40) | ITGB3ITGA2BPRMT5WDR77ALDH1A1 | |
| Acetic Acid SCHEMBL9317585 | 0.79 | ITGB3 (0.57) | ITGB3ITGA2BPRMT5WDR77 | |
| SCHEMBL7329425 | 0.78 | ITGB3 (0.43) | ITGB3ITGA2BGABRA1GABRG2GABRB3 | |
| SCHEMBL7332526 | 0.77 | ITGB3 (0.46) | ITGB3ITGA2BGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII b?III a? RECEPTOR. | GENENTECH INC (US) | 1994-08-17 | — | — | EP | disclosed |