Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 6/20 | 0.37 |
| ▸ | F2 | P00734 | 4/20 | 0.37 |
| ▸ | TNF | P01375 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317712 | 0.92 | ITGB3 (0.57) | ITGB3ITGA2BPRMT5WDR77F10 | |
| SCHEMBL7330253 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BF10F2PRSS1 | |
| Acetic Acid SCHEMBL9317585 | 0.90 | ITGB3 (0.57) | ITGB3ITGA2BPRMT5WDR77F10 | |
| SCHEMBL9318262 | 0.90 | ITGB3 (0.51) | ITGB3ITGA2BPRMT5WDR77F10 | |
| Acetic Acid SCHEMBL9318257 | 0.87 | ITGB3 (0.62) | ITGB3ITGA2BPRMT5WDR77MAPT | |
| SCHEMBL7326457 | 0.85 | ITGB3 (0.56) | ITGB3ITGA2BF10F2 | |
| SCHEMBL7331720 | 0.85 | ITGB3 (0.67) | ITGB3ITGA2BF10F2TNF | |
| SCHEMBL9317827 | 0.84 | ITGB3 (0.42) | ITGB3ITGA2BPRMT5WDR77HDAC6 | |
| Acetic Acid SCHEMBL7331206 | 0.83 | ITGB3 (0.56) | ITGB3ITGA2BF10F2 | |
| SCHEMBL7358608 | 0.82 | ITGB3 (0.57) | ITGB3ITGA2BPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII b?III a? RECEPTOR. | GENENTECH INC (US) | 1994-08-17 | — | — | EP | disclosed |