Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318225 | 0.92 | AGTR1 (0.51) | AGTR1AGTR2PPARG | |
| Hydrochloric Acid SCHEMBL9426589 | 0.91 | AGTR1 (0.51) | AGTR1AGTR2PPARG | |
| SCHEMBL9318747 | 0.89 | AGTR1 (0.47) | AGTR1 | |
| SCHEMBL9318062 | 0.88 | AGTR1 (0.45) | AGTR1 | |
| SCHEMBL9319121 | 0.86 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL2774605 | 0.84 | AGTR2 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9318254 | 0.84 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9320315 | 0.84 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9318727 | 0.83 | — | — | |
| SCHEMBL9319099 | 0.82 | AGTR1 (0.45) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514197-A1 | Anti-hypertensive benzofuran derivatives substituted by N-imidazolyl-methyl groups which are condensed with optionally nitrogen containing, six-membered rings | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | claimed |
| US-5317023-A | 2-Phenyl-(imidazo(4,5-b)pyridyl-methyl-) derivatives; hypertensive agents; cognition activators | GLAXO GROUP LIMITED (GB) | 1994-05-31 | — | — | US | disclosed |
| EP-0514197-A1 | Anti-hypertensive benzofuran derivatives substituted by N-imidazolyl-methyl groups which are condensed with optionally nitrogen containing, six-membered rings | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |