Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | BRD2 | P25440 | 2/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318279 | 0.90 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPK1KDM4ELMNAPOLB | |
| SCHEMBL9318183 | 0.88 | MAPK1 (0.49) | SMN1; SMN2MAPK1KDM4ELMNAPOLB | |
| SCHEMBL10691699 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPK1KDM4ELMNAPOLB | |
| SCHEMBL9318694 | 0.88 | MAPK1 (0.48) | SMN1; SMN2MAPK1KDM4ELMNAPOLB | |
| SCHEMBL9318035 | 0.87 | MAPK1 (0.48) | SMN1; SMN2MAPK1KDM4ELMNAPOLB | |
| SCHEMBL9318082 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPK1KDM4ELMNAPOLB | |
| SCHEMBL9318321 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPK1KDM4ELMNAPOLB | |
| Hydrochloric Acid SCHEMBL9318358 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPK1KDM4ELMNAPOLB | |
| SCHEMBL9318253 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPK1KDM4ELMNAPOLB | |
| SCHEMBL10855700 | 0.83 | ADORA2B (0.58) | SMN1; SMN2MAPK1LMNAPOLBTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264081-B1 | Oxadiazolyl alkyl purin derivatives, their preparation and their use in pharmaceutical compositions | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1994-01-05 | — | — | EP | claimed |
| EP-0264081-A2 | Oxadiazolyl alkyl purin derivatives, their preparation and their use in pharmaceutical compositions | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1988-04-20 | — | — | EP | claimed |