Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800575 | 0.87 | ALDH1A1 (0.50) | ALDH1A1GPR35TDP1MAPK1MAPT | |
| SCHEMBL10785960 | 0.83 | GPR35 (0.52) | ALDH1A1GPR35TDP1MAPK1MAPT | |
| SCHEMBL30669890 | 0.80 | ALDH1A1 (0.58) | ALDH1A1GPR35TDP1MAPK1MAPT | |
| SCHEMBL10447225 | 0.78 | ALDH1A1 (0.46) | ALDH1A1GPR35TDP1MAPK1MAPT | |
| SCHEMBL11800446 | 0.75 | ALDH1A1 (0.48) | ALDH1A1GPR35TDP1MAPK1MAPT | |
| SCHEMBL27715908 | 0.75 | KMT2A (0.45) | ALDH1A1GPR35TDP1MAPK1MAPT | |
| Trinitrotoluene SCHEMBL20676 | 0.75 | ALDH1A1 (0.61) | ALDH1A1GPR35TDP1MAPK1MAPT | |
| Trinitrotoluene SCHEMBL891182 | 0.75 | ALDH1A1 (0.61) | ALDH1A1GPR35TDP1MAPK1MAPT | |
| SCHEMBL2822069 | 0.74 | ALDH1A1 (0.58) | ALDH1A1GPR35TDP1MAPK1MAPT | |
| Trinitrotoluene SCHEMBL14966251 | 0.73 | ALDH1A1 (0.59) | ALDH1A1GPR35TDP1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385990-B1 | PRODUCTION OF HEXANITROSTILBENE (HNS) | SECR DEFENCE BRIT (GB) | 1994-01-05 | — | — | EP | disclosed |
| EP-0294131-B1 | PRODUCTION OF HEXANITROSTILBENE (HNS) | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOV. OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1992-09-09 | — | — | EP | disclosed |
| EP-0385990-A1 | PRODUCTION OF HEXANITROSTILBENE (HNS). | SECR DEFENCE BRIT (GB) | 1990-09-12 | — | — | EP | disclosed |
| WO-1988009784-A1 | PRODUCTION OF HEXANITROSTILBENE (HNS) | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) | 1988-12-15 | — | — | WO | disclosed |
| EP-0294131-A1 | Production of hexanitrostilbene (HNS) | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOV. OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1988-12-07 | — | — | EP | disclosed |
| EP-0132990-B1 | PRODUCTION OF HEXANITROSTILBENE (HNS) | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1987-09-02 | — | — | EP | disclosed |
| US-4626606-A | Production of hexanitrostilbene (HNS) | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1986-12-02 | — | — | US | disclosed |
| US-4626606-A | Production of hexanitrostilbene (HNS) | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1986-12-02 | — | — | US | disclosed |
| EP-0132990-A2 | Production of hexanitrostilbene (HNS) | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1985-02-13 | — | — | EP | disclosed |
| EP-0132990-A2 | Production of hexanitrostilbene (HNS) | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1985-02-13 | — | — | EP | disclosed |