Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29843057 | 1.00 | CYP19A1 (0.44) | CYP19A1SRD5A1SRD5A2 | |
| SCHEMBL7802581 | 0.84 | SRD5A1 (0.58) | SRD5A1SRD5A2 | |
| SCHEMBL7527164 | 0.84 | SRD5A1 (0.58) | SRD5A1SRD5A2 | |
| SCHEMBL9152806 | 0.79 | SRD5A2 (0.50) | SRD5A2 | |
| SCHEMBL8682897 | 0.78 | SRD5A1 (0.42) | SRD5A1SRD5A2 | |
| SCHEMBL8585461 | 0.74 | SRD5A1 (0.44) | SRD5A1SRD5A2 | |
| SCHEMBL8996738 | 0.74 | SRD5A1 (0.46) | SRD5A1SRD5A2 | |
| SCHEMBL6176597 | 0.74 | MBOAT4 (0.48) | CYP19A1 | |
| SCHEMBL21816929 | 0.72 | SRD5A1 (0.38) | CYP19A1SRD5A1SRD5A2 | |
| SCHEMBL8076029 | 0.71 | NR1I3 (0.47) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576603-A1 | PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC HYPERPLASIA, CONTAINING A 5 ALPHA-REDUCTASE INHIBITOR AND AN ANTIANDROGEN | MERCK & CO. INC. (US) | 1994-01-05 | — | — | EP | disclosed |