Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12820764 | 0.78 | KDM4C (0.41) | KDM4CLMNAPOLBMAPTALDH1A1 | |
| SCHEMBL8813561 | 0.74 | GAA (0.42) | POLBMAPTALDH1A1GRIN2DGRIN3B | |
| Alcohol SCHEMBL10696050 | 0.73 | ALDH1A1 (0.39) | LMNAMAPTALDH1A1TSHRMAPK1 | |
| SCHEMBL1187005 | 0.72 | — | — | |
| SCHEMBL31074740 | 0.72 | ALDH1A1 (0.43) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11732631 | 0.72 | MAPT (0.34) | LMNAPOLBMAPTALDH1A1MEN1 | |
| SCHEMBL9762515 | 0.70 | ALDH1A1 (0.51) | LMNAPOLBMAPTALDH1A1MEN1 | |
| SCHEMBL29793430 | 0.70 | ALDH1A1 (0.37) | LMNAPOLBMAPTALDH1A1GRIN2D | |
| SCHEMBL12441774 | 0.70 | MAPT (0.35) | LMNAMAPTALDH1A1GRIN2DGRIN3B | |
| SCHEMBL11617678 | 0.68 | ALDH1A1 (0.34) | LMNAMAPTALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555352-A4 | AGENTS FOR THE TREATMENT OF DISEASES CAUSED BY PARASITIC PROTOZOA AND NEOPLASTIC DISEASES | HEALTH RESEARCH INC (US) | 1994-12-14 | — | — | EP | disclosed |