Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1187005 | 0.90 | — | — | |
| SCHEMBL28809178 | 0.77 | — | — | |
| SCHEMBL11617678 | 0.77 | ALDH1A1 (0.34) | ALDH1A1MAPK1LMNATHRBTSHR | |
| SCHEMBL8813561 | 0.76 | GAA (0.42) | ALDH1A1MAPK1SMN1; SMN2ATMMAPT | |
| SCHEMBL31074740 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MAPTGAA | |
| Ethyl Nicotinate SCHEMBL7711056 | 0.73 | L3MBTL1 (0.50) | ALDH1A1MAPK1LMNATSHRMAPT | |
| SCHEMBL5182829 | 0.73 | TSHR (0.38) | ALDH1A1MAPK1LMNATHRBTSHR | |
| SCHEMBL9318283 | 0.73 | KDM4C (0.38) | ALDH1A1MAPK1LMNATSHRSMN1; SMN2 | |
| SCHEMBL9953612 | 0.73 | MAPK1 (0.34) | MAPK1ATMMAPTCHRM1 | |
| SCHEMBL5045818 | 0.73 | MAPK1 (0.34) | ALDH1A1MAPK1LMNATHRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110448633-A | The pharmaceutical composition and preparation method thereof for treating vaginitis | LIU YUMEI | 2019-11-15 | — | — | CN | claimed |
| EP-0176831-B1 | FAST RESPONSE, HIGH RATE, GAS DIFFUSION ELECTRODE AND METHOD OF MAKING SAME | ELTECH SYSTEMS CORPORATION (US) | 1988-11-09 | — | — | EP | claimed |
| US-12285404-B2 | Prevention of rosacea inflammation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-04-29 | — | — | US | disclosed |
| US-20230181518-A1 | PREVENTION OF ROSACEA INFLAMMATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-06-15 | — | — | US | disclosed |
| CN-110448633-A | The pharmaceutical composition and preparation method thereof for treating vaginitis | LIU YUMEI | 2019-11-15 | — | — | CN | disclosed |
| CN-110448633-A | The pharmaceutical composition and preparation method thereof for treating vaginitis | LIU YUMEI | 2019-11-15 | — | — | CN | disclosed |
| CN-209584043-U | Metronidazole produces the conversion recyclable device containing formic acid wastewater | HECHI JINXING BIOTECHNOLOGY CO LTD | 2019-11-05 | — | — | CN | disclosed |
| CN-109776425-A | The conversion recyclable device of formic acid solvent in metronidazole production process | 河池市金兴生物科技有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-103315995-B | Use alpha-hydroxy carbonyl compounds as reducing agent | 莫沃斯技术有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-108593768-A | One kind is for hush pipe weld seam detection platform in carbon tetrachloride processing equipment | 徐州工程学院 | 2018-09-28 | — | — | CN | disclosed |
| CN-104297239-A | Rapid detection kit and detection method for metronidazole in cosmetics | ZHONGSHAN DINGSHENG BIOTECHNOLOGY CO LTD | 2015-01-21 | — | — | CN | disclosed |