Tert-Butanol

Tert-Butanol

SCHEMBL9318334

CC(C)(C)CC(=O)CC(=O)O.CC(C)(C)O

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.46
CHRM1 P11229 1/20 0.46
TBXA2R P21731 1/20 0.46
ADRA1A P35348 1/20 0.46
TSHR P16473 2/20 0.39
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 2/20 0.39
CYP2D6 P10635 1/20 0.39
LDHA P00338 1/20 0.38
SRR Q9GZT4 1/20 0.38
ALDH1A1 P00352 2/20 0.35
CPT2 P23786 2/20 0.34
KDM4E B2RXH2 2/20 0.34
FFAR1 O14842 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ACLY P53396 3/20 0.33
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL52091 0.95 HMGCR (0.43) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL9298951 0.95 HMGCR (0.43) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL31555508 0.82 HMGCR (0.48) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL27761178 0.82 HMGCR (0.48) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL14282026 0.81 HMGCR (0.36) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL23148171 0.78 HMGCR (0.44) HMGCRCHRM1TBXA2RADRA1ATSHR
Malonic Acid SCHEMBL28112208 0.78 LDHA (0.64) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL8762434 0.76 ABCC4 (0.37) HMGCRCHRM1TBXA2RADRA1AALDH1A1
SCHEMBL5483788 0.76 LDHA (0.44) HMGCRCHRM1TBXA2RADRA1ATSHR
Malonic Acid SCHEMBL27550870 0.75 LDHA (0.60) HMGCRCHRM1TBXA2RADRA1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0586391-A1 DIARYLIDE PIGMENT COMPOSITION. SUN CHEMICAL CORP (US) 1994-03-16 EP disclosed
WO-1992013922-A1 DIARYLIDE PIGMENT COMPOSITION SUN CHEMICAL CORPORATION (US) 1992-08-20 WO disclosed