Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 3/20 | 0.37 |
| ▸ | CPT2 | P23786 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31555508 | 0.78 | HMGCR (0.48) | LDHASRRALDH1A1HMGCRCHRM1 | |
| SCHEMBL27761178 | 0.78 | HMGCR (0.48) | LDHASRRALDH1A1HMGCRCHRM1 | |
| SCHEMBL16323032 | 0.78 | HMGCR (0.38) | LDHASRRHMGCRCHRM1TBXA2R | |
| Tert-Butanol SCHEMBL9318334 | 0.76 | HMGCR (0.46) | LDHASRRALDH1A1HMGCRCHRM1 | |
| SCHEMBL52091 | 0.74 | HMGCR (0.43) | LDHASRRALDH1A1HMGCRCHRM1 | |
| SCHEMBL9298951 | 0.74 | HMGCR (0.43) | LDHASRRALDH1A1HMGCRCHRM1 | |
| SCHEMBL5211347 | 0.74 | LDHA (0.42) | LDHASRRALDH1A1HMGCRCHRM1 | |
| SCHEMBL8828363 | 0.74 | LDHA (0.42) | LDHASRRALDH1A1HMGCRCHRM1 | |
| SCHEMBL8849629 | 0.74 | LMNA (0.35) | LDHASRRALDH1A1HMGCRCHRM1 | |
| SCHEMBL23148171 | 0.74 | HMGCR (0.44) | LDHASRRALDH1A1HMGCRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070048337-A1 | Aldol-crosslinked polymeric hydrogel adhesives | ACTAMAX SURGICAL MATERIALS, LLC | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070048337-A1 | Aldol-crosslinked polymeric hydrogel adhesives | ALDOA, ADSL, ALDH1A2 | LDHA 123/4885SRR 2568/4885ALDH1A1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.