Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzoquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoquinone SCHEMBL4943047 | 0.81 | TDP1 (0.61) | BLMTDP1ALDH1A1BCHEPOLB | |
| Benzoquinone SCHEMBL27939443 | 0.81 | TDP1 (0.61) | BLMTDP1ALDH1A1BCHEPOLB | |
| Benzoquinone SCHEMBL27730092 | 0.81 | TDP1 (0.61) | BLMTDP1ALDH1A1BCHEPOLB | |
| Benzoquinone SCHEMBL3238193 | 0.81 | TDP1 (0.61) | BLMTDP1ALDH1A1BCHEPOLB | |
| Benzoquinone SCHEMBL28528775 | 0.78 | TDP1 (0.57) | BLMTDP1ALDH1A1BCHEPOLB | |
| Benzoquinone SCHEMBL27878726 | 0.78 | TDP1 (0.57) | BLMTDP1ALDH1A1BCHEPOLB | |
| Benzoquinone SCHEMBL27390105 | 0.78 | TDP1 (0.57) | BLMTDP1ALDH1A1BCHEPOLB | |
| SCHEMBL2622 | 0.77 | PTGS1 (0.60) | BLMTDP1ALDH1A1APEX1PTGS1 | |
| SCHEMBL21777928 | 0.77 | PTGS1 (0.60) | BLMTDP1ALDH1A1APEX1PTGS1 | |
| Benzoquinone SCHEMBL8035204 | 0.75 | TDP1 (0.53) | BLMTDP1ALDH1A1BCHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324815-A | Polyaniline | NITTO DENKO CORPORATION (JP) | 1994-06-28 | — | — | US | disclosed |