Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2622 | 1.00 | PTGS1 (0.60) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL2521154 | 0.95 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL2524419 | 0.95 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL5763087 | 0.95 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| Hydrochloric Acid SCHEMBL14053301 | 0.95 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL11359486 | 0.95 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL2288880 | 0.95 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL20607658 | 0.95 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| Water SCHEMBL162527 | 0.95 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL459169 | 0.95 | PTGS1 (0.56) | PTGS1PDE4ALMNASLC6A6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3302435-B1 | LIPOSOME LOADING | PLUMB PHARMACEUTICALS INC (US) | 2023-03-08 | — | — | EP | claimed |
| US-20260041665-A1 | J-Tp Protection | HUYABIO INT LLC (US) | 2026-02-12 | — | — | US | disclosed |
| US-20250041223-A1 | LIPOSOME LOADING | PLUMB PHARMACEUTICALS, INC. | 2025-02-06 | — | — | US | disclosed |
| US-12059499-B2 | Liposome loading | PLUMB PHARMACEUTICALS, INC. (US) | 2024-08-13 | — | — | US | disclosed |
| CN-116916889-A | Inhalation-type imatinib for lung high-pressure field | 联合治疗公司 | 2023-10-20 | — | — | CN | disclosed |
| EP-4212148-A1 | LIPOSOME LOADING | Plumb Pharmaceuticals, Inc. (US) | 2023-07-19 | — | — | EP | disclosed |
| CN-115813923-A | Compounds for the treatment of neurogenic orthostatic hypotension | 施万生物制药研发IP有限责任公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115770244-A | Compounds for the treatment of neurogenic orthostatic hypotension | 施万生物制药研发IP有限责任公司 | 2023-03-10 | — | — | CN | disclosed |
| EP-3302435-B1 | LIPOSOME LOADING | PLUMB PHARMACEUTICALS INC (US) | 2023-03-08 | — | — | EP | disclosed |
| US-20210130330-A1 | SOLID FORMS OF CERDULATINIB | ALEXION PHARMACEUTICALS, INC. | 2021-05-06 | — | — | US | disclosed |
| WO-2020047198-A1 | SALTS OF AN LSD1 INHIBITOR AND PROCESSES FOR PREPARING THE SAME | INCYTE CORPORATION (US) | 2020-03-05 | — | — | WO | disclosed |
| CN-101278888-B | Oral care compositions and methods | COLGATE PALMOLIVE CO | 2015-04-08 | — | — | CN | disclosed |
| CN-1756524-B | Oral care compositions and methods | COLGATE PALMOLIVE CO | 2013-11-06 | — | — | CN | disclosed |
| CN-102895127-A | Oral care compositions and methods | COLGATE PALMOLIVE CO | 2013-01-30 | — | — | CN | disclosed |
| CN-101278888-A | Oral care compositions and methods | COLGATE PALMOLIVE CO (US) | 2008-10-08 | — | — | CN | disclosed |
| CN-1756524-A | Oral care compositions and methods | COLGATE PALMOLIVE CO (US) | 2006-04-05 | — | — | CN | disclosed |
| CN-1128947-A | Soft-shelled gelatin encapsulated particles | SMITHKLINE BEECHAM CORP (US) | 1996-08-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260041665-A1 | J-Tp Protection | CACNA1I, KCNN3, CACNA1G | PTGS1 2207/4885PDE4A 3455/4885LMNA 367/4885 |
| US-20210130330-A1 | SOLID FORMS OF CERDULATINIB | CLK1, CLK2, DCLK1 | PTGS1 3576/4885PDE4A 2433/4885LMNA 2112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.