Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.72 |
| ▸ | G6PD | P11413 | 7/20 | 0.51 |
| ▸ | GABRP | O00591 | 4/20 | 0.51 |
| ▸ | GABRD | O14764 | 4/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.51 |
| ▸ | GABRE | P78334 | 4/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8164233 | 0.84 | SRD5A2 (0.65) | SRD5A2G6PDGABRPGABRDGABRA1 | |
| SCHEMBL8164230 | 0.84 | SRD5A2 (0.65) | SRD5A2G6PDGABRPGABRDGABRA1 | |
| SCHEMBL8164216 | 0.84 | SRD5A2 (1.00) | SRD5A2G6PDGABRPGABRDGABRA1 | |
| SCHEMBL8164220 | 0.84 | SRD5A2 (1.00) | SRD5A2G6PDGABRPGABRDGABRA1 | |
| SCHEMBL10698961 | 0.76 | GRIN1 (0.68) | SRD5A2G6PDGABRPGABRDGABRA1 | |
| SCHEMBL11667307 | 0.76 | GRIN1 (0.68) | SRD5A2G6PDGABRPGABRDGABRA1 | |
| SCHEMBL9318780 | 0.75 | SRD5A2 (0.73) | SRD5A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9501460 | 0.75 | SRD5A2 (0.62) | SRD5A2G6PDGABRPGABRDGABRA1 | |
| SCHEMBL4740475 | 0.74 | GPBAR1 (0.64) | SRD5A2CYP3A4KMT2ACYP2C9MEN1 | |
| SCHEMBL9066592 | 0.74 | SRD5A2 (0.61) | SRD5A2G6PDGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576603-A1 | PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC HYPERPLASIA, CONTAINING A 5 ALPHA-REDUCTASE INHIBITOR AND AN ANTIANDROGEN | MERCK & CO. INC. (US) | 1994-01-05 | — | — | EP | disclosed |