Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11592710 | 0.94 | TSHR (0.41) | TSHRCYP3A4TP53TPMTALDH1A1 | |
| SCHEMBL17143891 | 0.82 | RAPGEF4 (0.32) | TSHR | |
| SCHEMBL17144353 | 0.82 | RAPGEF4 (0.33) | TSHR | |
| SCHEMBL2945314 | 0.82 | TSHR (0.32) | TSHR | |
| SCHEMBL28434608 | 0.77 | NOTUM (0.38) | TSHRCYP3A4ALDH1A1FFAR4 | |
| SCHEMBL356245 | 0.75 | — | — | |
| SCHEMBL1312095 | 0.73 | ALDH1A1 (0.45) | TSHRCYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL98355 | 0.73 | — | — | |
| SCHEMBL1040544 | 0.71 | — | — | |
| 1,3,5-Trichlorobenzene SCHEMBL429512 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE48335-E1 | Polymyxin derivatives as antimicrobial compounds | MONASH UNIVERSITY (AU) | 2020-12-01 | — | — | US | claimed |
| CN-106414480-B | Polymyxin derivatives as antimicrobial compounds | 莫纳什大学 | 2020-08-04 | — | — | CN | claimed |
| EP-2586769-B1 | METHOD FOR PRODUCING (1R, 2S)-1-AMINO-2-VINYL CYCLOPROPANE CARBOXYLIC ACID ESTER THAT HAS IMPROVED OPTICAL PURITY | KANEKA CORP (JP) | 2019-01-16 | — | — | EP | claimed |
| CN-109105380-A | A kind of herbicidal composition of penoxsuam and KIH 6127 | 安徽圣丰生化有限公司 | 2019-01-01 | — | — | CN | claimed |
| EP-2963023-B1 | PROCESS FOR PREPARING 5-AMINO-1, 2, 3-TRIAZOLE OROTATE DERIVATIVES | TACTICAL THERAPEUTICS INC (US) | 2018-04-18 | — | — | EP | claimed |
| CN-107915621-A | A kind of preparation method of 3,5 dichloro-benzoyl | 苏州盖德精细材料有限公司 | 2018-04-17 | — | — | CN | claimed |
| US-20170137469-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2017-05-18 | — | — | US | claimed |
| EP-3126376-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | Monash University (AU) | 2017-02-08 | — | — | EP | claimed |
| US-9234087-B2 | Preparation for initiating radical reactions | UNITED INITIATORS GMBH & CO. KG (DE) | 2016-01-12 | — | — | US | claimed |
| EP-2963023-A1 | PROCESS FOR PREPARING 5-AMINO-1, 2, 3-TRIAZOLE OROTATE DERIVATIVES | Tactical Therapeutics Inc. (US) | 2016-01-06 | — | — | EP | claimed |
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | claimed |
| US-5583248-A | Amino acid derivatives having antiviral activity | HOFFMANN-LA ROCHE INC. (US) | 1996-12-10 | — | — | US | claimed |
| EP-0512343-B1 | Amino acid derivatives and their use as anti-viral agents | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | EP | claimed |
| US-5430041-A | Amino acid derivatives having antiviral activity | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | claimed |
| US-5380834-A | Side effect reduction | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-01-10 | — | — | US | claimed |
| EP-0560055-A1 | Immuno-suppressing enepyranose derivatives | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1993-09-15 | — | — | EP | claimed |
| EP-0512343-A2 | Amino acid derivatives and their use as anti-viral agents | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | claimed |
| US-4868241-A | POLYVINYL ALCOHOL MODIFIED WITH BENZOIC ACID DERIVATIVE | AMERICAN CYANAMID COMPANY (US) | 1989-09-19 | — | — | US | claimed |
| EP-0231922-A2 | Electron beam and X-ray resists | AMERICAN CYANAMID COMPANY (US) | 1987-08-12 | — | — | EP | claimed |
| EP-0035792-B1 | CERTAIN 1-(3,5-DICHLOROBENZOYL)-3-PHENYLPYRAZOLINES AND THEIR USE AS MILDEWICIDES | STAUFFER CHEMICAL COMPANY (US) | 1984-06-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137469-A1 | POLYMYXIN DERIVATIVES AS ANTIMICROBIAL COMPOUNDS | VIP, PEPD, NRDC | TSHR 4543/4885CYP3A4 4416/4885TP53 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.