Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 7/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.32 |
| ▸ | PKM | P14618 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712510 | 0.85 | NPC1 (0.43) | NPC1RAB9AGABRA1GABRB2MEN1 | |
| SCHEMBL7166175 | 0.80 | NPC1 (0.36) | NPC1RAB9AGABRA1GABRB2MEN1 | |
| SCHEMBL7164578 | 0.79 | POLB (0.33) | GABRA1GABRB2MEN1KMT2APKM | |
| SCHEMBL9603768 | 0.79 | NPC1 (0.42) | NPC1RAB9AGABRA1GABRB2MEN1 | |
| SCHEMBL28234016 | 0.77 | NPC1 (0.40) | NPC1RAB9AGABRA1GABRB2MEN1 | |
| SCHEMBL9323446 | 0.74 | NPC1 (0.38) | NPC1RAB9AGABRA1GABRB2MEN1 | |
| SCHEMBL7698243 | 0.74 | TNKS (0.46) | NPC1RAB9AGABRA1GABRB2MEN1 | |
| SCHEMBL7172273 | 0.73 | ACE2 (0.33) | NPC1RAB9AALDH1A1TP53ACE2 | |
| SCHEMBL29384819 | 0.72 | NPC1 (0.58) | NPC1RAB9AGABRA1GABRB2MEN1 | |
| SCHEMBL285279 | 0.72 | NPC1 (0.58) | NPC1RAB9AGABRA1GABRB2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286772-A | Synergistic compositions for the prevention of polymer degradation | THE UNIVERSITY OF UTAH (US) | 1994-02-15 | — | — | US | disclosed |
| US-4076764-A | HEAT AND RADIATION RESISTANCE | SHELL OIL COMPANY (US) | 1978-02-28 | — | — | US | disclosed |