SCHEMBL9319014

SCHEMBL9319014

NC(c1ccccc1)(C(c1ccccc1)c1ccccc1)C(N)(c1ccccc1)C(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.48
DPP4 P27487 2/20 0.42
F2 P00734 1/20 0.42
HTR2A P28223 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
TSHR P16473 3/20 0.36
ALDH1A1 P00352 1/20 0.36
HRH1 P35367 1/20 0.36
KIF11 P52732 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11772008 0.80 KCNN4 (0.48) KCNN4DPP4F2HTR2ATAAR1
SCHEMBL15940336 0.76 KCNN4 (0.44) KCNN4DPP4F2HTR2ATAAR1
SCHEMBL21590130 0.76 KCNN4 (0.44) KCNN4DPP4F2HTR2ATAAR1
SCHEMBL2302238 0.76 DPP4 (0.48) KCNN4DPP4F2HTR2ATAAR1
SCHEMBL544573 0.74 TSHR (0.39) KCNN4DPP4F2HTR2ATAAR1
SCHEMBL17931025 0.74 TSHR (0.39) KCNN4DPP4F2HTR2ATAAR1
SCHEMBL352841 0.72 TAAR1 (0.46) DPP4F2HTR2ATAAR1ALDH1A1
SCHEMBL6743744 0.71 AOC3 (0.47) KCNN4DPP4F2CYP1A2CYP2D6
SCHEMBL1059023 0.70 MAPK1 (0.42) KCNN4TAAR1ALDH1A1HRH1
SCHEMBL1059025 0.70 MAPK1 (0.42) KCNN4TAAR1ALDH1A1HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6073066-A None JP disclosed
JP-H0673066-A ASYMMETRIC COPPER COMPLEX, ITS PRODUCTION AND PRODUCTION OF OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID COMPOUNDS USING THE COPPER COMPLEX SUMITOMO CHEM CO LTD 1994-03-15 JP disclosed