SCHEMBL9319031

SCHEMBL9319031

CCOC(=O)C(Cc1ccc(C)cc1)N(C)C(=O)Cc1ccc(Cl)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC1 P07992 2/20 0.47
ERCC4 Q92889 2/20 0.47
CYP3A4 P08684 2/20 0.45
CYP2C9 P11712 1/20 0.45
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
GAA P10253 1/20 0.40
SIGMAR1 Q99720 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
ALOX15 P16050 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9321088 0.95 ERCC1 (0.49) ERCC1ERCC4CYP3A4CYP2C9PRSS1
SCHEMBL9318734 0.91 PRSS1 (0.51) ERCC1ERCC4CYP3A4CYP2C9PRSS1
SCHEMBL9319482 0.88 CYP3A4 (0.47) ERCC1ERCC4CYP3A4CYP2C9PRSS1
SCHEMBL9319856 0.84 CYP3A4 (0.47) ERCC1ERCC4CYP3A4CYP2C9PRSS1
SCHEMBL9318567 0.83 KMT2A (0.39) CYP3A4CYP2C9SIGMAR1L3MBTL1CYP1A2
SCHEMBL9321286 0.83 TSHR (0.45) SMN1; SMN2
SCHEMBL9319873 0.83 CYP3A4 (0.45) ERCC1ERCC4CYP3A4CYP2C9GAA
SCHEMBL9318726 0.82 LMNA (0.53) ERCC1ERCC4CYP3A4CYP2C9PRSS1
SCHEMBL9318604 0.81 EPHX2 (0.41) L3MBTL1PPARGPPARAALDH1A1HTT
SCHEMBL9319227 0.81 TSHR (0.45) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5350861-A Insecticides, acaricides, fungicides, antimycotic agents BAYER AKTIENGESELLSCHAFT (DE) 1994-09-27 US disclosed