Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318734 | 0.92 | PRSS1 (0.51) | CYP3A4CYP2C9PRSS1PRSS2PRSS3 | |
| SCHEMBL9321088 | 0.90 | ERCC1 (0.49) | CYP3A4CYP2C9PRSS1PRSS2PRSS3 | |
| SCHEMBL9318726 | 0.89 | LMNA (0.53) | CYP3A4CYP2C9PRSS1PRSS2PRSS3 | |
| SCHEMBL9319031 | 0.88 | ERCC1 (0.47) | CYP3A4CYP2C9PRSS1PRSS2PRSS3 | |
| SCHEMBL9318523 | 0.88 | ALOX5 (0.42) | PRSS1PRSS2PRSS3LMNASMN1; SMN2 | |
| SCHEMBL9319856 | 0.86 | CYP3A4 (0.47) | CYP3A4CYP2C9PRSS1PRSS2PRSS3 | |
| SCHEMBL9318605 | 0.85 | ALOX5 (0.45) | CYP3A4CYP2C9TP53SMN1; SMN2MAPK1 | |
| SCHEMBL9319910 | 0.83 | GRM5 (0.42) | LMNASMN1; SMN2MAPTMAPK1ALOX5 | |
| SCHEMBL9319338 | 0.81 | CCR5 (0.45) | CYP3A4CYP2C9ERCC1ERCC4LMNA | |
| SCHEMBL8073847 | 0.79 | PPARG (0.44) | LMNASMN1; SMN2MAPTMAPK1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350861-A | Insecticides, acaricides, fungicides, antimycotic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1994-09-27 | — | — | US | disclosed |