Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890725 | 1.00 | MTNR1A (0.35) | MTNR1AMTNR1BCETPHIF1AHSD17B10 | |
| SCHEMBL8888254 | 0.89 | CA12 (0.34) | MAPTKDM4E | |
| SCHEMBL8888853 | 0.88 | CETP (0.33) | CETPHSD17B10MAPTLMNAKDM4E | |
| SCHEMBL8891507 | 0.80 | CDC25B (0.37) | MTNR1AMTNR1BCETPMAPTCDC25B | |
| SCHEMBL8889029 | 0.80 | CETP (0.33) | CETP | |
| SCHEMBL8888644 | 0.74 | CYP3A4 (0.31) | — | |
| SCHEMBL8890048 | 0.68 | MAPT (0.35) | CETPHSD17B10MAPTCDC25BLMNA | |
| SCHEMBL8887535 | 0.66 | ST6GAL1 (0.36) | — | |
| SCHEMBL8939971 | 0.64 | FFAR4 (0.41) | CETPHSD17B10LMNAGAAKDM4E | |
| SCHEMBL5723031 | 0.64 | PDE4A (0.42) | CETPHSD17B10LMNAKDM4ECASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5366986-A | SPIROBENZOFURAN-2(3H)-CYCLOALKANE COMPOUNDS | T CELL SCIENCES, INC. (US) | 1994-11-22 | — | — | US | disclosed |