Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.36 |
| ▸ | FUT6 | P51993 | 1/20 | 0.36 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.36 |
| ▸ | ST3GAL1 | Q11201 | 1/20 | 0.36 |
| ▸ | ST3GAL3 | Q11203 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889029 | 0.86 | CETP (0.33) | — | |
| SCHEMBL8888644 | 0.83 | CYP3A4 (0.31) | — | |
| SCHEMBL8887766 | 0.75 | IDO1 (0.32) | ST6GAL1FUT6FUT5ST3GAL1ST3GAL3 | |
| SCHEMBL3609698 | 0.71 | PIK3CD (0.35) | ST6GAL1FUT6FUT5ST3GAL1ST3GAL3 | |
| SCHEMBL8888853 | 0.69 | CETP (0.33) | — | |
| SCHEMBL9319161 | 0.66 | MTNR1A (0.35) | — | |
| SCHEMBL8890725 | 0.66 | MTNR1A (0.35) | — | |
| SCHEMBL8887291 | 0.60 | ALDH1A1 (0.32) | — | |
| SCHEMBL4230579 | 0.56 | ALDH1A1 (0.47) | — | |
| SCHEMBL4241344 | 0.56 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656659-A | SUBSTITUTED DIHYDROBENZOFURAN COMPOUNDS | T CELL SCIENCES, INC. (US) | 1997-08-12 | — | — | US | disclosed |
| US-5401767-A | Compounds which inhibit complement and/or suppress immune activity | T CELL SCIENCES, INC. (US) | 1995-03-28 | — | — | US | disclosed |
| US-5366986-A | SPIROBENZOFURAN-2(3H)-CYCLOALKANE COMPOUNDS | T CELL SCIENCES, INC. (US) | 1994-11-22 | — | — | US | disclosed |
| US-5173499-A | 4-Methoxyspiro(benzofuran-2,1'-cyclohexane)-7-N-methyl-carboxamides and derivatives; autoimmune diseases; antiischemic agents; respiratory system disorders | T CELL SCIENCES, INC. (US) | 1992-12-22 | — | — | US | disclosed |