Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.72 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711385 | 0.88 | PGR (0.57) | MAPTMCOLN3CA12CA9LMNA | |
| SCHEMBL11441218 | 0.86 | MAPT (0.74) | MAPTMCOLN3CA12CA9LMNA | |
| SCHEMBL2008337 | 0.85 | MAPT (1.00) | MAPTMCOLN3CA12CA9LMNA | |
| SCHEMBL15480590 | 0.82 | MAPT (0.68) | MAPTMCOLN3CA12CA9LMNA | |
| SCHEMBL13543262 | 0.82 | MAPT (0.68) | MAPTMCOLN3CA12CA9LMNA | |
| SCHEMBL17174235 | 0.80 | MAPT (0.82) | MAPTMCOLN3CA12CA9LMNA | |
| SCHEMBL6302212 | 0.80 | MAPT (0.82) | MAPTMCOLN3CA12CA9LMNA | |
| SCHEMBL18031174 | 0.80 | MAPT (0.82) | MAPTMCOLN3CA12CA9LMNA | |
| SCHEMBL7311605 | 0.78 | GAA (0.64) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL2517845 | 0.78 | MAPT (0.55) | MAPTLMNAHTTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5346904-A | BRONCHODILATOR AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1994-09-13 | — | — | US | disclosed |
| US-4211883-A | Process for the production of p-(N-methyl)-aminobenzoyl-L-glutamic acid | LONZA, LTD. (CH) | 1980-07-08 | — | — | US | disclosed |