Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114049 | 0.82 | AKR1C3 (0.56) | AKR1C3AKR1C2AKR1C1AKR1C4TTR | |
| SCHEMBL19615026 | 0.79 | AKR1C4 (0.50) | AKR1C3AKR1C2AKR1C1AKR1C4TTR | |
| SCHEMBL9318199 | 0.76 | AKR1C4 (0.47) | AKR1C3AKR1C2AKR1C1AKR1C4TTR | |
| SCHEMBL67463 | 0.76 | CYP3A4 (0.62) | AKR1C3AKR1C2AKR1C1AKR1C4TTR | |
| SCHEMBL28729095 | 0.71 | AKR1C3 (0.73) | AKR1C3AKR1C2AKR1C1AKR1C4PTPN1 | |
| SCHEMBL9304917 | 0.69 | AKR1C3 (0.44) | AKR1C3AKR1C2AKR1C1AKR1C4TTR | |
| SCHEMBL29387062 | 0.69 | AKR1C3 (1.00) | AKR1C3AKR1C2AKR1C1AKR1C4TTR | |
| SCHEMBL330545 | 0.69 | AKR1C3 (1.00) | AKR1C3AKR1C2AKR1C1AKR1C4TTR | |
| SCHEMBL16050418 | 0.68 | AKR1C4 (0.52) | AKR1C3AKR1C2AKR1C1AKR1C4TTR | |
| SCHEMBL825071 | 0.67 | HSPA5 (0.57) | TTRPTPN1ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290919-A | Physiological oxygen carrier, artificial blood | THE UNIVERSITY OF MARYLAND BALTIMORE (US) | 1994-03-01 | — | — | US | disclosed |