SCHEMBL11114049

SCHEMBL11114049

O=C(O)c1ccc(C(=O)O)c(Cc2cc(Br)cc(Br)c2O)c1Cc1cc(Br)cc(Br)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.56
AKR1C2 P52895 3/20 0.56
AKR1C1 Q04828 3/20 0.56
AKR1C4 P17516 2/20 0.56
TTR P02766 2/20 0.48
PTPN1 P18031 6/20 0.47
LMNA P02545 1/20 0.41
HSPD1 P10809 1/20 0.41
HSPE1 P61604 1/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PTPN2 P17706 3/20 0.41
PTPN6 P29350 3/20 0.41
ALDH1A1 P00352 2/20 0.40
POLB P06746 2/20 0.40
MAPT P10636 2/20 0.40
HSD17B10 Q99714 2/20 0.40
HPGD P15428 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19615026 0.83 AKR1C4 (0.50) AKR1C3AKR1C2AKR1C1AKR1C4TTR
SCHEMBL9319407 0.82 AKR1C3 (0.50) AKR1C3AKR1C2AKR1C1AKR1C4TTR
SCHEMBL9318199 0.81 AKR1C4 (0.47) AKR1C3AKR1C2AKR1C1AKR1C4TTR
SCHEMBL67463 0.76 CYP3A4 (0.62) AKR1C3AKR1C2AKR1C1AKR1C4TTR
SCHEMBL29387062 0.73 AKR1C3 (1.00) AKR1C3AKR1C2AKR1C1AKR1C4TTR
SCHEMBL330545 0.73 AKR1C3 (1.00) AKR1C3AKR1C2AKR1C1AKR1C4TTR
SCHEMBL16050418 0.72 AKR1C4 (0.52) AKR1C3AKR1C2AKR1C1AKR1C4TTR
SCHEMBL9398447 0.71 AKR1C3 (0.96) AKR1C3AKR1C2AKR1C1AKR1C4TTR
SCHEMBL9019697 0.71 AKR1C3 (0.96) AKR1C3AKR1C2AKR1C1AKR1C4TTR
SCHEMBL9398455 0.71 AKR1C3 (0.96) AKR1C3AKR1C2AKR1C1AKR1C4TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570600-B2 Multifunctional linker compounds 20Bloc, Inc. (US) 2026-03-10 US disclosed
US-20250243148-A1 MULTIFUNCTIONAL LINKER COMPOUNDS 20Bloc, Inc. 2025-07-31 US disclosed
US-4438198-A IMMOBILIZED ENZYMES ON FIBRIN IN AGAROSE SUSPENSION TRIMEDYNE, INC. (US) 1984-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243148-A1 MULTIFUNCTIONAL LINKER COMPOUNDS F13A1, MRPL21, SRRM2 AKR1C3 2131/4885AKR1C2 2561/4885AKR1C1 2180/4885
US-12570600-B2 Multifunctional linker compounds CHN2, RCC2, COG1 AKR1C3 1268/4885AKR1C2 1693/4885AKR1C1 1392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.