SCHEMBL825071

SCHEMBL825071

Oc1ccccc1Cc1cc(Br)cc(Br)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.57
LMNA P02545 2/20 0.48
TTR P02766 1/20 0.48
MEN1 O00255 5/20 0.47
KMT2A Q03164 5/20 0.47
MAPT P10636 4/20 0.47
CYP3A4 P08684 2/20 0.45
TSHR P16473 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
PKM P14618 1/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2C19 P33261 2/20 0.44
HIF1A Q16665 2/20 0.44
CYP2C9 P11712 1/20 0.44
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
PLEC Q15149 1/20 0.43
KEAP1 Q14145 1/20 0.43
CA12 O43570 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67463 0.84 CYP3A4 (0.62) LMNATTRMEN1KMT2AMAPT
SCHEMBL16320313 0.79 LMNA (0.43) LMNATTRMEN1KMT2AMAPT
SCHEMBL7774969 0.77 HSPA5 (0.73) HSPA5TSHRCYP2D6HIF1AKEAP1
SCHEMBL49745 0.76 HSPA5 (1.00) HSPA5LMNAMAPTCYP3A4TSHR
SCHEMBL29357407 0.76 HSPA5 (1.00) HSPA5LMNAMAPTCYP3A4TSHR
Ammonia Solution, Strong SCHEMBL28323965 0.73 HSPA5 (0.94) HSPA5LMNAMAPTCYP3A4TSHR
SCHEMBL5852726 0.73 HSPA5 (0.94) HSPA5LMNAMAPTCYP3A4TSHR
SCHEMBL29839938 0.73 HSPA5 (0.94) HSPA5LMNAMAPTCYP3A4TSHR
SCHEMBL7809667 0.73 HSPA5 (0.94) HSPA5LMNAMAPTCYP3A4TSHR
SCHEMBL13416170 0.73 HIF1A (0.55) HSPA5LMNAMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2714763-B1 EPOXY RESINS WITH HIGH THERMAL STABILITY AND TOUGHNESS HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2017-03-01 EP disclosed
US-9051498-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-9051498-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-9051415-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-9051415-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-20140296447-A1 Epoxy Resins With High Thermal Stability and Toughness Huntsman Advanced Materials Americans LLC (US) 2014-10-02 US disclosed
US-20140296447-A1 Epoxy Resins With High Thermal Stability and Toughness Huntsman Advanced Materials Americans LLC (US) 2014-10-02 US disclosed
US-20140069583-A1 Epoxy Resins With High Thermal Stability and Toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2014-03-13 US disclosed
US-20140069583-A1 Epoxy Resins With High Thermal Stability and Toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2014-03-13 US disclosed
US-8142101-B2 Hydrocarbon-adsorbing porous pavement structure Reynolds Presto Products Inc. (US) 2012-03-27 US disclosed
US-8043982-B2 Basalt particle-containing compositions and articles for protective coatings and ballistic shield mats/tiles/protective building components U.S. WIND FARMING, INC. (US) 2011-10-25 US disclosed
US-20100285269-A1 BASALT PARTICLE-CONTAINING COMPOSITIONS AND ARTICLES FOR PROTECTIVE COATINGS AND BALLISTIC SHIELD MATS/TILES/PROTECTIVE BUILDING COMPONENTS U.S. WIND FARMING, INC. (US) 2010-11-11 US disclosed
US-20100285269-A1 BASALT PARTICLE-CONTAINING COMPOSITIONS AND ARTICLES FOR PROTECTIVE COATINGS AND BALLISTIC SHIELD MATS/TILES/PROTECTIVE BUILDING COMPONENTS U.S. WIND FARMING, INC. (US) 2010-11-11 US disclosed
US-20100012004-A1 Basalt particle-containing compositions and articles for protective coatings and ballistic shield mats/tiles/protective building components U.S. WIND FARMING INC. (US) 2010-01-21 US disclosed
US-20090067924-A1 HYDROCARBON-ADSORBING POROUS PAVEMENT STRUCTURE KAUL CORPORATION (US) 2009-03-12 US disclosed
US-20090067924-A1 HYDROCARBON-ADSORBING POROUS PAVEMENT STRUCTURE KAUL CORPORATION (US) 2009-03-12 US disclosed
US-20070224401-A1 Basalt particle-containing articles for ballistic shield mats/tiles/protective building components U.S. WIND FARMING INC. (US) 2007-09-27 US disclosed
US-20070224401-A1 Basalt particle-containing articles for ballistic shield mats/tiles/protective building components U.S. WIND FARMING INC. (US) 2007-09-27 US disclosed
US-20070154643-A1 Extrusion coating compositions and method VALSPAR SOURCING, INC. (US) 2007-07-05 US disclosed
US-20070154643-A1 Extrusion coating compositions and method VALSPAR SOURCING, INC. (US) 2007-07-05 US disclosed