Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12487467 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL19001345 | 0.85 | NPC1 (0.42) | ALDH1A1MAPTL3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL11024908 | 0.81 | KDM4A (0.48) | ALDH1A1MAPTL3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL28973338 | 0.81 | KDM4E (0.61) | ALDH1A1MAPTL3MBTL1HPGDTDP1 | |
| SCHEMBL10085785 | 0.81 | P2RX7 (0.54) | ALDH1A1MAPTL3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL9319745 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPTL3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL10258703 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL17882450 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL19049435 | 0.79 | NPC1 (0.43) | ALDH1A1 | |
| SCHEMBL12753630 | 0.77 | CNR2 (0.51) | ALDH1A1MAPTL3MBTL1TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334724-A | Preparation of substituted 2-chloropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-02 | — | — | US | disclosed |
| US-5010201-A | Process for the preparation of substituted 2-chloropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |