SCHEMBL9319628

SCHEMBL9319628

CON(C)C(=O)Nc1ccc(N)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.70
KMT2A Q03164 3/20 0.70
PKM P14618 3/20 0.70
TDP1 Q9NUW8 3/20 0.70
RAB9A P51151 2/20 0.70
MAPT P10636 3/20 0.52
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
TSHR P16473 1/20 0.44
CYP2C19 P33261 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
KDM1A O60341 1/20 0.43
HPGD P15428 1/20 0.42
KDM4E B2RXH2 1/20 0.42
GLA P06280 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10425059 0.84 MEN1 (0.72) MEN1KMT2APKMTDP1RAB9A
SCHEMBL14629465 0.84 RAB9A (0.72) MEN1KMT2APKMTDP1RAB9A
Monolinuron SCHEMBL65568 0.82 RAB9A (1.00) MEN1KMT2APKMTDP1RAB9A
Monolinuron SCHEMBL1701381 0.82 RAB9A (1.00) MEN1KMT2APKMTDP1RAB9A
Metobromuron SCHEMBL53871 0.82 KMT2A (1.00) MEN1KMT2APKMTDP1RAB9A
Metobromuron SCHEMBL8536617 0.82 KMT2A (1.00) MEN1KMT2APKMTDP1RAB9A
SCHEMBL10669709 0.81 MEN1 (0.69) MEN1KMT2APKMTDP1RAB9A
SCHEMBL3649968 0.81 TSHR (0.66) MEN1KMT2APKMTDP1RAB9A
SCHEMBL17356369 0.79 MEN1 (0.66) MEN1KMT2APKMTDP1RAB9A
Metobromuron SCHEMBL20425338 0.79 KMT2A (0.93) MEN1KMT2APKMTDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6336470-A None JP disclosed
JP-H06336470-A SUBSTITUTED CARBAMOYLARYLUREA COMPOUND, ITS PRODUCTION AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT MITSUI PETROCHEM IND LTD 1994-12-06 JP disclosed