SCHEMBL14629465

SCHEMBL14629465

CON(C)C(=O)Nc1ccc(C)cc1

nearest known ligand 0.72

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.72
MEN1 O00255 3/20 0.72
KMT2A Q03164 3/20 0.72
TDP1 Q9NUW8 2/20 0.72
PKM P14618 1/20 0.72
MAPT P10636 2/20 0.50
ALDH1A1 P00352 2/20 0.50
POLB P06746 1/20 0.50
NPC1 O15118 3/20 0.48
HTT P42858 1/20 0.48
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TSHR P16473 1/20 0.46
KIF11 P52732 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11221817 0.91 MEN1 (0.60) RAB9AMEN1KMT2ATDP1PKM
SCHEMBL11111401 0.88 KMT2A (0.57) RAB9AMEN1KMT2ATDP1PKM
SCHEMBL10425059 0.85 MEN1 (0.72) RAB9AMEN1KMT2ATDP1PKM
Monolinuron SCHEMBL65568 0.84 RAB9A (1.00) RAB9AMEN1KMT2ATDP1PKM
Monolinuron SCHEMBL1701381 0.84 RAB9A (1.00) RAB9AMEN1KMT2ATDP1PKM
SCHEMBL9319628 0.84 MEN1 (0.70) RAB9AMEN1KMT2ATDP1PKM
Metobromuron SCHEMBL53871 0.84 KMT2A (1.00) RAB9AMEN1KMT2ATDP1PKM
Metobromuron SCHEMBL8536617 0.84 KMT2A (1.00) RAB9AMEN1KMT2ATDP1PKM
SCHEMBL10669709 0.83 MEN1 (0.69) RAB9AMEN1KMT2ATDP1PKM
SCHEMBL7901625 0.82 KMT2A (0.51) RAB9AMEN1KMT2ATDP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070020642-A1 Structural interaction fingerprint BIOGEN IDEC MA INC. 2007-01-25 US disclosed