SCHEMBL9319786

SCHEMBL9319786

Nc1ccc(N=Nc2ccccc2Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.59
RAB9A P51151 7/20 0.59
MEN1 O00255 7/20 0.59
KMT2A Q03164 7/20 0.59
HTT P42858 2/20 0.59
PKM P14618 1/20 0.59
TDP1 Q9NUW8 7/20 0.56
NPC1 O15118 6/20 0.56
L3MBTL1 Q9Y468 5/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
ALDH1A1 P00352 2/20 0.47
LMNA P02545 2/20 0.47
POLB P06746 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MAPK1 P28482 4/20 0.46
TP53 P04637 2/20 0.46
CYP3A4 P08684 2/20 0.46
TSHR P16473 2/20 0.46
HTR3E A5X5Y0 2/20 0.44
HTR3B O95264 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10409225 1.00 MAPT (0.59) MAPTRAB9AMEN1KMT2AHTT
SCHEMBL11318232 0.85 MAPT (0.73) MAPTRAB9AMEN1KMT2AHTT
SCHEMBL1405330 0.83 ALDH1A1 (0.57) MAPTRAB9AMEN1KMT2AHTT
SCHEMBL29820042 0.83 ALDH1A1 (0.57) MAPTRAB9AMEN1KMT2AHTT
SCHEMBL29820211 0.83 ALDH1A1 (0.57) MAPTRAB9AMEN1KMT2AHTT
SCHEMBL1405328 0.83 ALDH1A1 (0.57) MAPTRAB9AMEN1KMT2AHTT
SCHEMBL11792182 0.82 MEN1 (0.48) MAPTRAB9AMEN1KMT2AHTT
SCHEMBL11792188 0.82 MEN1 (0.48) MAPTRAB9AMEN1KMT2AHTT
SCHEMBL11650083 0.80 MAPT (0.56) MAPTRAB9AMEN1KMT2AHTT
SCHEMBL11149961 0.80 MEN1 (0.59) MAPTRAB9AMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105152963-B A kind of method using halogenated aromatic primary amine and aromatic amine reaction generation azobenzene compound 岭南师范学院 2017-12-15 CN disclosed
EP-0294330-B1 Cationic disazo dyes CIBA GEIGY AG (CH) 1994-01-12 EP disclosed
US-4921945-A Disazo dyes containing an acetoacetabukube coupling component and a quaternized aminoalkylene aminocarbonyl group bound to it CIBA-GEIGY CORPORATION (US) 1990-05-01 US disclosed
EP-0294330-A2 Cationic disazo dyes CIBA-GEIGY AG (CH) 1988-12-07 EP disclosed
US-4225493-A FOR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
US-4208324-A Disperse diaminopyridine-3-azo dyestuffs CIBA-GEIGY CORPORATION (US) 1980-06-17 US disclosed
US-4083847-A Transiently water-soluble disperse mono-azo dyes containing a diamino-methylene-carbacyl group CIBA-GEIGY CORPORATION (US) 1978-04-11 US disclosed
US-4068085-A YELLOW AND RED ON POLYESTERS AND ACRYLICS CIBA-GEIGY CORPORATION (US) 1978-01-10 US disclosed
US-4066637-A BASIC DIAMINOPYRIDINE-(3)-AZO DYESTUFFS CIBA-GEIGY CORPORATION (US) 1978-01-03 US disclosed
US-3988312-A TETRAKISAZO DYES CIBA-GEIGY CORPORATION (US) 1976-10-26 US disclosed
US-3987026-A POLYESTERS CIBA-GEIGY CORPORATION (US) 1976-10-19 US disclosed
US-3945991-A Heterocyclic azo compounds containing a quaternated hydrazide group CIBA-GEIGY AG (CH) 1976-03-23 US disclosed