Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.73 |
| ▸ | MEN1 | O00255 | 7/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.73 |
| ▸ | RAB9A | P51151 | 6/20 | 0.73 |
| ▸ | PKM | P14618 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.70 |
| ▸ | NPC1 | O15118 | 7/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | HBB | P68871 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655985 | 0.89 | RAB9A (0.70) | MAPTMEN1KMT2ARAB9APKM | |
| SCHEMBL8655983 | 0.89 | RAB9A (0.70) | MAPTMEN1KMT2ARAB9APKM | |
| SCHEMBL29683217 | 0.89 | RAB9A (0.70) | MAPTMEN1KMT2ARAB9APKM | |
| SCHEMBL12277762 | 0.85 | MAPT (0.64) | MAPTMEN1KMT2ARAB9APKM | |
| SCHEMBL10409225 | 0.85 | MAPT (0.59) | MAPTMEN1KMT2ARAB9APKM | |
| SCHEMBL28036462 | 0.85 | MEN1 (0.61) | MAPTMEN1KMT2ARAB9APKM | |
| SCHEMBL9073594 | 0.85 | TDP1 (0.66) | MAPTMEN1KMT2ARAB9APKM | |
| SCHEMBL9319786 | 0.85 | MAPT (0.59) | MAPTMEN1KMT2ARAB9APKM | |
| SCHEMBL9073596 | 0.85 | TDP1 (0.66) | MAPTMEN1KMT2ARAB9APKM | |
| SCHEMBL11794663 | 0.84 | MAPT (1.00) | MAPTMEN1KMT2ARAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271288-A | TETRACARBOXYLIC ACID BONDED TO ARYLENE MOIETY VIA METHYLENE GROUPS | THE DOW CHEMICAL COMPANY (US) | 1981-06-02 | — | — | US | disclosed |