SCHEMBL9319930

SCHEMBL9319930

COc1ccc(P(c2ccc(OC)c(C)c2)c2ccc(OC)c(C)c2)cc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.43
MAPT P10636 3/20 0.41
ALOX15 P16050 1/20 0.41
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
PTGS2 P35354 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
NQO2 P16083 1/20 0.38
CRHBP P24387 2/20 0.38
CRHR2 Q13324 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 1/20 0.38
CYP19A1 P11511 1/20 0.38
KDM4E B2RXH2 1/20 0.38
PDGFRB P09619 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17829472 0.92 TDP1 (0.46) ACHEMAPTALDH1A1CYP3A4PTGS2
SCHEMBL11791887 0.83 ACHE (0.40) ACHEMAPTALOX15ALDH1A1CYP3A4
SCHEMBL28035632 0.81 CA2 (0.52) ACHEALDH1A1CYP3A4PTGS2CA12
SCHEMBL29751099 0.81 CA2 (0.52) ACHEALDH1A1CYP3A4PTGS2CA12
SCHEMBL29751097 0.81 CA2 (0.52) ACHEALDH1A1CYP3A4PTGS2CA12
SCHEMBL16689835 0.79 NQO2 (0.38) ACHEMAPTALOX15ALDH1A1CYP3A4
SCHEMBL8994697 0.77 TDP1 (0.48) ACHEALDH1A1CYP3A4CA12CA1
SCHEMBL29362051 0.75 TDP1 (0.46) MAPTALDH1A1CYP3A4PTGS2CA12
Hydrochloric Acid SCHEMBL11656824 0.74 TDP1 (0.44) ACHEMAPTALDH1A1CYP3A4CA12
SCHEMBL29352952 0.73 ACHE (0.68) ACHEMAPTALOX15ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0300772-B1 Catalyst for polymerization of conjugated diene and process for producing conjugated diene polymer JAPAN SYNTHETIC RUBBER CO LTD (JP) 1994-01-19 EP disclosed
US-4954125-A COORDINATION CATALYST CONTAINING COBALT COMPOUND, ORGANIC PHOSPHINE COMPOUND, AND ORGANOALUMINUM COMPOUND JAPAN SYNTHETIC RUBBER COMPANY, LTD. (JP) 1990-09-04 US disclosed
EP-0300772-A1 Catalyst for polymerization of conjugated diene and process for producing conjugated diene polymer JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-01-25 EP disclosed