Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28434347 | 0.81 | KDM4E (0.65) | CYP1A2HTTALDH1A1GAAKMT2A | |
| SCHEMBL28231531 | 0.81 | CYP1A2 (0.48) | PDGFRBPDGFRACYP1A2TDP1ALDH1A1 | |
| SCHEMBL9319496 | 0.80 | KDM4E (0.57) | PDGFRBPDGFRAALDH1A1GAAKMT2A | |
| SCHEMBL8001647 | 0.79 | CYP1A2 (0.56) | CYP1A2TDP1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL2210778 | 0.78 | CYP1A2 (0.54) | CYP1A2HTTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL27613559 | 0.78 | CYP1A2 (0.54) | CYP1A2ALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL28881748 | 0.77 | KDM4E (0.47) | PDGFRBPDGFRACYP1A2HTTALDH1A1 | |
| SCHEMBL28428697 | 0.77 | TSHR (0.64) | CYP1A2TDP1ALDH1A1GAALMNA | |
| SCHEMBL8643558 | 0.77 | KDM4E (0.67) | PDGFRBPDGFRAALDH1A1GAAKMT2A | |
| SCHEMBL1208379 | 0.77 | CYP1A2 (0.53) | CYP1A2HTTTDP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371220-A | Bicyclo-heterocyclic intermediates for cephalosporin compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-12-06 | — | — | US | disclosed |
| US-5232918-A | Bactericides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-03 | — | — | US | disclosed |
| US-5019570-A | Antibioics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-28 | — | — | US | disclosed |