Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001647 | 0.85 | CYP1A2 (0.56) | TSHRCYP1A2MAPTKDM4ETDP1 | |
| SCHEMBL2210778 | 0.84 | CYP1A2 (0.54) | TSHRCYP1A2MAPTKDM4EALDH1A1 | |
| SCHEMBL14339761 | 0.83 | MAPT (0.48) | TSHRMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL1208379 | 0.82 | CYP1A2 (0.53) | TSHRCYP1A2MAPTKDM4ETDP1 | |
| SCHEMBL2001591 | 0.82 | ALDH1A1 (0.65) | TSHRCYP1A2MAPTKDM4ENPSR1 | |
| SCHEMBL28434347 | 0.81 | KDM4E (0.65) | CYP1A2MAPTKDM4ELMNANPSR1 | |
| SCHEMBL28231530 | 0.81 | ALDH1A1 (0.48) | TSHRCYP1A2MAPTKDM4EALDH1A1 | |
| SCHEMBL28428705 | 0.80 | CYP1A2 (0.50) | TSHRCYP1A2MAPTKDM4ELMNA | |
| SCHEMBL1998568 | 0.79 | CYP1A2 (0.49) | TSHRCYP1A2MAPTKDM4ELMNA | |
| SCHEMBL2002271 | 0.79 | CYP1A2 (0.49) | TSHRCYP1A2MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108314647-B | Preparation method of quinoline-2-formic acid and quinoline-2-formic acid derivative | 华中科技大学 | 2020-06-26 | — | — | CN | claimed |
| CN-108314647-B | Preparation method of quinoline-2-formic acid and quinoline-2-formic acid derivative | 华中科技大学 | 2020-06-26 | — | — | CN | disclosed |