Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342388 | 0.85 | HDAC8 (0.55) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL28231530 | 0.85 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL8001647 | 0.84 | CYP1A2 (0.56) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL2210778 | 0.82 | CYP1A2 (0.54) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL13905450 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1HPGDCTSLCTSB | |
| SCHEMBL28428697 | 0.81 | TSHR (0.64) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL2001591 | 0.81 | ALDH1A1 (0.65) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL9319975 | 0.81 | PDGFRB (0.53) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL1208379 | 0.81 | CYP1A2 (0.53) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL8806346 | 0.81 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108314647-B | Preparation method of quinoline-2-formic acid and quinoline-2-formic acid derivative | 华中科技大学 | 2020-06-26 | — | — | CN | claimed |
| CN-108314647-B | Preparation method of quinoline-2-formic acid and quinoline-2-formic acid derivative | 华中科技大学 | 2020-06-26 | — | — | CN | disclosed |